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Abstract
Background/aims: The aim of this study was to examine a plausible correlation between venous and arterial blood gas values in acidotic patients with chronic uremia or diabetic ketoacidosis (DKA). Methods: A total of 152 arterial and 152 venous blood samples from uremic patients (n = 100), DKA patients (n = 21) and healthy controls (n = 31) were analyzed for measurements of blood gas and acid-base status. Results: The means of arterial and venous pH, and arterial and venous HCO- values for the uremic patients were 7.17 0.14, 7.13 0.14, 10.13 4.26 and 11.86 + 4.23 mmol/l, respectively. The respective mean differences between arterial and venous pH values and arterial and venous HCO- values were 0.04 0.02 and -1.72 0.42 mmol/l, respectively, for these patients. The means of the laboratory findings of DKA patients were arterial pH, 7.15 0.15; venous pH, 7.10 0.15; arterial HCO-, 8.57 5.71 mmol/I and venous HCO-, 10.46 5.73 mmol/l. The respective mean differences between arterial and venous pH and arterial
and venous HCO- for this group were calculated to be 0.05 0.01 and -1.88 0.41 mmol/l. In the healthy controls, the means of arterial and venous pH, and arterial and venous HCO- values were 7.39 0.02, 7.34 0.02, 24.91 0.82 and 26.57 0.83 mmol/I, respectively. For the healthy controls the mean differences between the respective values in arterial and venous pH, and arterial and venous HCO- were 0.05 0.01 and -1.66 0.58 mmol/l. Although in healthy controls the correlation between arterial and venous pH values (r2: 0.595) and arterial and venous HCO- values (r2: 0.552) were moderate, these correlations were significantly increased in both the acidotic patient group (r2: 0.979 and 0.990) and the DKA group (r2: 0.989 and 0.995) Conclusion: A venous blood sample can be used to evaluate the acidbase status in uremic and DKA patients.
Copyright 2000 S. Karger AG, Basel
Key Words
Arterial blood gas values Venous blood gas HC03 Uremic acidosis Diabetic ketoacidosis
Introduction
The determination of arterial blood gas values is considered essential in the emergency department evaluation of uremic patients and patients with diabetic ketoacidosis (DKA) [1, 2]. Risks of arterial blood sampling include pain, artery damage, hemorrhage, aneurysm formation, thrombosis of the artery, infection or loss of...